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A Multi-center, Randomized, Double-blind, Placebo-controlled, Parallel Group, Phase III Study to Evaluate the Efficacy and Safety of LNP023 in Primary IgA Nephropathy Patients

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Trial Profile

A Multi-center, Randomized, Double-blind, Placebo-controlled, Parallel Group, Phase III Study to Evaluate the Efficacy and Safety of LNP023 in Primary IgA Nephropathy Patients

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 10 Jun 2026

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At a glance

  • Drugs Iptacopan (Primary)
  • Indications IgA nephropathy
  • Focus Registrational; Therapeutic Use
  • Acronyms APPLAUSE; APPLAUSE-IgAN
  • Sponsors Novartis; Novartis Pharma A.G.; Novartis Pharmaceuticals

Most Recent Events

  • 10 Jun 2026 New source identified and integrated (Clinical Trials Information System).
  • 26 May 2026 According to a Novartis media release,data from this study will be presented at European Renal Association (ERA 2026 ) Congress in Glasgow, June 3-6.
  • 29 Mar 2026 Primary endpoint . (Annualized total estimated Glomerular Filtration Rate (eGFR) slope over 24 months).)has been met,According to a Novartis media releaseAccording to a Novartis media release.

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