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Phase 1 Study to Evaluate Safety and Efficacy of APR-548 in Combination With Azacitidine for the Treatment of TP53-Mutant Myelodysplastic Syndromes

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Trial Profile

Phase 1 Study to Evaluate Safety and Efficacy of APR-548 in Combination With Azacitidine for the Treatment of TP53-Mutant Myelodysplastic Syndromes

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 18 Aug 2022

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At a glance

  • Drugs APR-548 (Primary) ; Azacitidine (Primary)
  • Indications Myelodysplastic syndromes
  • Focus Adverse reactions; First in man
  • Sponsors Aprea Therapeutics
  • Most Recent Events

    • 11 Aug 2022 According to an Aprea media release, enrollment in the first dosing cohort was completed.
    • 20 Jul 2022 Status changed from suspended to discontinued as per sponsor decision.
    • 01 Jun 2022 Status changed from recruiting to suspended due to sponsor decision.

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