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A Phase 1 Study of NBTXR3 Activated by Radiotherapy With Concurrent Chemotherapy for Adenocarcinoma of the Esophagus

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A Phase 1 Study of NBTXR3 Activated by Radiotherapy With Concurrent Chemotherapy for Adenocarcinoma of the Esophagus

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 24 May 2024

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At a glance

  • Drugs Capecitabine (Primary) ; Carboplatin (Primary) ; Docetaxel (Primary) ; Fluorouracil (Primary) ; Folinic acid (Primary) ; Hafnium oxide (Primary) ; Oxaliplatin (Primary) ; Paclitaxel (Primary)
  • Indications Adenocarcinoma; Oesophageal cancer
  • Focus Adverse reactions
  • Sponsors Nanobiotix

    • Most Recent Events

    • 21 May 2024 According to a Nanobiotix media release,Dose escalation part ongoing,the company expected to complete dose escalation part and initiation of dose expansion part in this year. first data will be presented in 2025.
    • 13 Nov 2023 According to a Nanobiotix media release, determination of RP2D in NSCLC trial, Completion of enrollment in Phase 1b dose expansion trial in pancreatic cancer, Initial Phase 1b/2 data in esophageal cancer data expected in 2024.
    • 08 Nov 2023 Planned End Date changed from 31 Oct 2022 to 31 Oct 2025.
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