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Phase 1-2 Trial of ADI-PEG 20 Plus Radiotherapy and Temozolomide in Subjects with Newly Diagnosed Glioblastoma Multiforme (GBM)

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Trial Profile

Phase 1-2 Trial of ADI-PEG 20 Plus Radiotherapy and Temozolomide in Subjects with Newly Diagnosed Glioblastoma Multiforme (GBM)

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 30 Oct 2024

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At a glance

  • Drugs Pegargiminase (Primary) ; Temozolomide (Primary) ; Temozolomide (Primary)
  • Indications Glioblastoma
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms GBM
  • Sponsors Polaris Pharmaceuticals

    • Most Recent Events

    • 29 Sep 2022 Planned End Date changed from 31 Jul 2022 to 30 May 2027.
    • 29 Sep 2022 Planned primary completion date changed from 31 Jul 2022 to 28 Feb 2027.
    • 07 Jun 2022 Results (n=23) assessing major adverse events from cohort 1 and cohort 2 of this trial presented at the 58th Annual Meeting of the American Society of Clinical Oncology

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