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A Phase III Multicenter Randomized, Double-Blind, Double-Dummy, Parallel-Group Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Adult Patients With Relapsing Multiple Sclerosis

Trial Profile

A Phase III Multicenter Randomized, Double-Blind, Double-Dummy, Parallel-Group Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Adult Patients With Relapsing Multiple Sclerosis

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 10 Jun 2025

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At a glance

  • Drugs Fenebrutinib (Primary) ; Teriflunomide
  • Indications Multiple sclerosis
  • Focus Registrational; Therapeutic Use
  • Acronyms FENhance 2
  • Sponsors Roche

Most Recent Events

  • 03 Jun 2025 Planned End Date changed from 27 Nov 2025 to 9 Jul 2027.
  • 03 Jun 2025 Planned primary completion date changed from 2 Oct 2025 to 5 Sep 2025.
  • 30 May 2025 According to a Roche media release, company is expecting results from this trial later this year.

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