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An Open Label, Single-Arm, Multi-center Phase Ib/II Study to Evaluate the Efficacy of Paclitaxel in Combination With Pembrolizumab and Olaparib as a Second Line Treatment in Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer With Homologous Recombination Repair (HRR) Mutation and Microsatellite Stable (MSS)

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An Open Label, Single-Arm, Multi-center Phase Ib/II Study to Evaluate the Efficacy of Paclitaxel in Combination With Pembrolizumab and Olaparib as a Second Line Treatment in Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer With Homologous Recombination Repair (HRR) Mutation and Microsatellite Stable (MSS)

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 30 Dec 2024

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At a glance

  • Drugs Olaparib (Primary) ; Paclitaxel (Primary) ; Pembrolizumab (Primary)
  • Indications Gastric cancer; Oesophageal cancer
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 24 Dec 2024 Planned End Date changed from 31 May 2023 to 31 May 2025.
    • 24 Dec 2024 Planned primary completion date changed from 31 Dec 2022 to 31 Dec 2024.
    • 24 Dec 2024 Status changed from not yet recruiting to recruiting.

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