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An Open Label, Single-Arm, Multi-center Phase Ib/II Study to Evaluate the Efficacy of Paclitaxel in Combination With Pembrolizumab and Olaparib as a Second Line Treatment in Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer With Homologous Recombination Repair (HRR) Mutation and Microsatellite Stable (MSS)

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An Open Label, Single-Arm, Multi-center Phase Ib/II Study to Evaluate the Efficacy of Paclitaxel in Combination With Pembrolizumab and Olaparib as a Second Line Treatment in Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer With Homologous Recombination Repair (HRR) Mutation and Microsatellite Stable (MSS)

Status: Not yet recruiting
Phase of Trial: Phase I/II

Latest Information Update: 04 Aug 2023

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At a glance

  • Drugs Olaparib (Primary) ; Paclitaxel (Primary) ; Pembrolizumab (Primary)
  • Indications Gastric cancer; Oesophageal cancer
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 29 Aug 2021 Planned End Date changed from 31 Dec 2022 to 31 May 2023.
    • 29 Aug 2021 Planned primary completion date changed from 31 Jul 2022 to 31 Dec 2022.
    • 29 Aug 2021 Planned initiation date changed from 1 May 2021 to 1 Oct 2021.

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