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Randomized Master Protocol for Immune Modulators for Treating COVID-19

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Trial Profile

Randomized Master Protocol for Immune Modulators for Treating COVID-19

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 02 Dec 2024

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At a glance

  • Drugs Abatacept (Primary) ; Cenicriviroc (Primary) ; Infliximab (Primary) ; Dexamethasone; Remdesivir
  • Indications COVID 2019 infections; COVID-19 pneumonia; SARS-CoV-2 acute respiratory disease
  • Focus Therapeutic Use
  • Acronyms ACTIV-1 IM

    • Most Recent Events

    • 10 Jul 2023 Results investigating whether abatacept, cenicriviroc, or infliximab provides benefit when added to standard care for COVID-19 pneumonia , published in the JAMA: the Journal of the American Medical Association
    • 02 Jun 2022 Results presented in a Bristol-Myers Squibb Media Release.
    • 02 Jun 2022 According to a Bristol-Myers Squibb media release, the full report on these data will be published in a peer-reviewed scientific journal. Given the positive findings from the topline data, Bristol Myers Squibb plans to discuss these data and potential next steps with the U.S. Food and Drug Administration.

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