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A Phase I, Open-label, First-in-human, Dose Escalation and Expansion Study to Evaluate the Safety, Tolerability and Pharmacokinetic Profile of Recombinant Humanized Anti-Trop2 mAb-Tub196 Conjugate in Patients With Advanced Solid Tumors.

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Trial Profile

A Phase I, Open-label, First-in-human, Dose Escalation and Expansion Study to Evaluate the Safety, Tolerability and Pharmacokinetic Profile of Recombinant Humanized Anti-Trop2 mAb-Tub196 Conjugate in Patients With Advanced Solid Tumors.

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 10 Jul 2023

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At a glance

  • Drugs JS 108 (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors Shanghai Junshi Biosciences

Most Recent Events

  • 04 Jul 2023 Status changed from recruiting to discontinued. Sponsor has adjusted study development plan and terminated this clinical study.
  • 01 Apr 2022 Planned End Date changed from 23 Nov 2022 to 23 Nov 2023.
  • 01 Apr 2022 Planned primary completion date changed from 23 Nov 2022 to 26 Oct 2023.

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