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A Randomized, 2-Arm, Open-Label, Ph-II Study of Abemaciclib Combined With ET w/ or w/o CT With Paclitaxel as 1L in Patients With Unresectable Locally Advanced or Metastatic HR(+)/HER2(-) BC With Aggressive Disease Criteria

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A Randomized, 2-Arm, Open-Label, Ph-II Study of Abemaciclib Combined With ET w/ or w/o CT With Paclitaxel as 1L in Patients With Unresectable Locally Advanced or Metastatic HR(+)/HER2(-) BC With Aggressive Disease Criteria

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 08 Aug 2024

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At a glance

  • Drugs Abemaciclib (Primary) ; Fulvestrant (Primary) ; Letrozole (Primary) ; Antineoplastics; Gonadotropin releasing hormone modulators; Paclitaxel
  • Indications Advanced breast cancer; HER2 negative breast cancer; Male breast cancer
  • Focus Therapeutic Use
  • Acronyms ABIGAIL

    • Most Recent Events

    • 28 Feb 2024 Planned End Date changed from 1 May 2024 to 30 Jun 2025.
    • 28 Feb 2024 Planned primary completion date changed from 1 Jan 2024 to 1 Jun 2024.
    • 15 Jan 2024 Status changed from recruiting to active, no longer recruiting.

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