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A Phase 2b, Double-Blind, Placebo-Controlled, Parallel-Groups, 36-Week, 2-Arm Trial to Assess the Safety, Tolerability, and Efficacy of Xanamem 10 mg Daily in Patients With Mild or Moderate Dementia Due to Alzheimer's Disease

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Trial Profile

A Phase 2b, Double-Blind, Placebo-Controlled, Parallel-Groups, 36-Week, 2-Arm Trial to Assess the Safety, Tolerability, and Efficacy of Xanamem 10 mg Daily in Patients With Mild or Moderate Dementia Due to Alzheimer's Disease

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 07 May 2024

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At a glance

  • Drugs UE 2343 (Primary)
  • Indications Alzheimer's disease; Dementia
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms XanaMIA
  • Sponsors Actinogen Medical
  • Most Recent Events

    • 15 Apr 2024 According to an Actinogen Medical media release, the trial has commenced at thirteen Australian sites and will subsequently expand to the USA. An interim analysis is planned for mid-2025 when approximately 100 patients reach 24 weeks of treatment, with final results anticipated in H1 2026.
    • 15 Apr 2024 According to an Actinogen Medical media release, the first patient has been randomized and treated in the XanaMIA phase 2b clinical trial in patients with biomarker-positive mild to moderate Alzheimer's disease (AD).
    • 13 Oct 2023 According to an Actinogen Medical media release, Enrolment of the first 100 patients will take place at Australian sites and initial efficacy and safety results from an administrative interim analysis will occur when approximately 100 patients reach 24 weeks of treatment.Final results are anticipated in the second half of 2025.
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