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A Multicenter, Phase 1/2 Study of Selinexor in Combination With Backbone Treatments or Novel Therapies in Patients With Relapsed or Refractory (RR) Diffuse Large B-Cell Lymphoma (DLBCL)

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Trial Profile

A Multicenter, Phase 1/2 Study of Selinexor in Combination With Backbone Treatments or Novel Therapies in Patients With Relapsed or Refractory (RR) Diffuse Large B-Cell Lymphoma (DLBCL)

Status: Suspended
Phase of Trial: Phase I/II

Latest Information Update: 02 Nov 2021

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At a glance

  • Drugs Bendamustine (Primary) ; Gemcitabine (Primary) ; Ibrutinib (Primary) ; Lenalidomide (Primary) ; Oxaliplatin (Primary) ; Polatuzumab vedotin (Primary) ; Rituximab (Primary) ; Selinexor (Primary) ; Tafasitamab (Primary) ; Venetoclax (Primary)
  • Indications Diffuse large B cell lymphoma
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Karyopharm Therapeutics
  • Most Recent Events

    • 04 Jun 2021 Status changed from recruiting to suspended.
    • 20 May 2021 Planned number of patients changed from 308 to 350.
    • 23 Dec 2020 Status changed from not yet recruiting to recruiting.

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