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GRECO-2: A Randomized, Phase 2b Study of GC4711 in Combination With Stereotactic Body Radiation Therapy (SBRT) in the Treatment of Unresectable or Borderline Resectable Nonmetastatic Pancreatic Cancer

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Trial Profile

GRECO-2: A Randomized, Phase 2b Study of GC4711 in Combination With Stereotactic Body Radiation Therapy (SBRT) in the Treatment of Unresectable or Borderline Resectable Nonmetastatic Pancreatic Cancer

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 23 May 2024

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At a glance

  • Drugs Rucosopasem manganese (Primary)
  • Indications Adenocarcinoma; Pancreatic cancer
  • Focus Therapeutic Use
  • Acronyms GRECO-2
  • Sponsors Galera Therapeutics

Most Recent Events

  • 14 Nov 2023 According to a Galera Therapeutics media release, the trial had enrolled 177 patients by the date of the decision to halt the trial.
  • 14 Nov 2023 According to a Galera Therapeutics media release, as of September 30, 2023, Galera had cash, cash equivalents and short-term investments of $28.4 million. Galera expects that its existing cash, cash equivalents and short-term investments, taking into account the discontinuation of the GRECO-1 and GRECO-2 trials, will enable Galera to fund its operating expenses and capital expenditure requirements into 2025.
  • 31 Oct 2023 According to a Galera Therapeutics media release, based on the futility analysis conducted based on 35 deaths with a data cutoff of October 9, 2023 of GRECO-2 trial, the company has decided to discontinue both GRECO trials.

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