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A Randomised, Double-blind, Placebo Controlled, Parallel Group Phase III Study to Assess the Clinical Efficacy and Safety of 100 mg SC Mepolizumab in Adults With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) / Eosinophilic Chronic Rhinosinusitis (ECRS) MERIT: Mepolizumab in Eosinophilic Chronic RhinosinusITis Study

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Trial Profile

A Randomised, Double-blind, Placebo Controlled, Parallel Group Phase III Study to Assess the Clinical Efficacy and Safety of 100 mg SC Mepolizumab in Adults With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) / Eosinophilic Chronic Rhinosinusitis (ECRS) MERIT: Mepolizumab in Eosinophilic Chronic RhinosinusITis Study

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 28 Nov 2024

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At a glance

  • Drugs Mepolizumab (Primary)
  • Indications Nasal polyps; Rhinosinusitis
  • Focus Registrational; Therapeutic Use
  • Acronyms MERIT
  • Sponsors GlaxoSmithKline; GSK

    • Most Recent Events

    • 25 Nov 2024 According to ClinicalTrials.gov by the U.S. National Institutes of Health, the primary endpoints have been replaced with four new threrapeutic (TU) endpoints.
    • 18 Nov 2024 Results presented in the GSK Media Release.
    • 18 Nov 2024 According to a GSK media release, Ministry of Health, Labour and Welfare (MHLW), Japan has approved Nucala (mepolizumab) for the treatment of chronic rhinosinusitis with nasal polyps (CRSwNP) in adult patients, limited to those who are inadequately controlled with standard treatment.

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