Trial Profile

An Open-label, Single-arm, Phase Ib/IIa Trial to Evaluate the Safety and Efficacy of the EP4 Receptor Antagonist CR6086 in Combination With the PD-1 Inhibitor Balstilimab (AGEN2034), in Patients With Pretreated Mismatch-repair-proficient and Microsatellite Stable Metastatic Colorectal Cancer, and Other Metastatic GI Cancers

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 09 Jun 2025

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At a glance

03 Jun 2025 Planned number of patients changed from 55 to 107.
03 Jun 2025 Planned End Date changed from 1 Sep 2026 to 1 Jun 2027.
03 Jun 2025 Planned primary completion date changed from 1 Mar 2025 to 1 Dec 2026.

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