Trial Profile

Pilot Feasibility and Efficacy Trial of a Novel Reversible LSD1 Inhibitor SP-2577 (Seclidemstat) Plus Pembrolizumab in Select SWI/SNF-mutant Gynecologic Cancers

Status: Withdrawn prior to enrolment

Phase of Trial: Phase I

Latest Information Update: 04 Dec 2025

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At a glance

Drugs Pembrolizumab (Primary) ; Seclidemstat (Primary)
Indications Carcinoma; Endometrial cancer; Ovarian cancer
Focus Adverse reactions; Therapeutic Use

Most Recent Events

13 Nov 2025 According to a Salarius Pharmaceuticals media release, Salarius Pharmaceuticals has merged with Decoy Therapeutics to form Decoy Therapeutics.
11 Feb 2022 Status changed from not yet recruiting to withdrawn prior to enrolment.
16 Nov 2021 Planned initiation date changed from 1 Oct 2021 to 31 Dec 2021.

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