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Open-Label Phase 1b/2 Study of Cetuximab Administered in Combination With LY3214996 (ERK 1/2 Inhibitor) or Cetuximab in Combination With LY3214996 and Abemaciclib in Patients With Metastatic, Anti-EGFR-Refractory Colorectal Cancer

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Trial Profile

Open-Label Phase 1b/2 Study of Cetuximab Administered in Combination With LY3214996 (ERK 1/2 Inhibitor) or Cetuximab in Combination With LY3214996 and Abemaciclib in Patients With Metastatic, Anti-EGFR-Refractory Colorectal Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 04 Jun 2024

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At a glance

  • Drugs Abemaciclib (Primary) ; Cetuximab (Primary) ; Temuterkib (Primary)
  • Indications Adenocarcinoma; Colon cancer; Colorectal cancer; Rectal cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 29 May 2024 Planned End Date changed from 31 Dec 2024 to 31 Dec 2025.
    • 29 May 2024 Planned primary completion date changed from 31 Dec 2024 to 31 Dec 2025.
    • 29 Oct 2023 Planned End Date changed from 31 Dec 2023 to 31 Dec 2024.

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