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Safety & Efficacy of Neoadjuvant Immunotherapy With Durvalumab (MEDI 4736) Combined With Neoadjuvant Chemotherapy (Gemcitabine/Cisplatin or Gemcitabine/Carboplatin) in Patients With Operable, High-risk, Localized Urothelial Carcinoma of the Upper Urinary Tract

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Trial Profile

Safety & Efficacy of Neoadjuvant Immunotherapy With Durvalumab (MEDI 4736) Combined With Neoadjuvant Chemotherapy (Gemcitabine/Cisplatin or Gemcitabine/Carboplatin) in Patients With Operable, High-risk, Localized Urothelial Carcinoma of the Upper Urinary Tract

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 27 Dec 2023

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At a glance

  • Drugs Carboplatin (Primary) ; Cisplatin (Primary) ; Durvalumab (Primary) ; Gemcitabine (Primary)
  • Indications Adenocarcinoma; Renal cancer; Squamous cell cancer; Ureteral neoplasms; Urogenital cancer
  • Focus Therapeutic Use
  • Acronyms iNDUCT

    • Most Recent Events

    • 01 Dec 2023 Trial design, published in the World Journal of Urology
    • 26 May 2023 Planned number of patients changed from 99 to 50.
    • 26 May 2023 Planned End Date changed from 1 Oct 2025 to 1 Oct 2026.

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