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A Phase 2 Study of Avutometinib (VS-6766) (Dual RAF/MEK Inhibitor) as a Single Agent and In Combination With Defactinib (FAK Inhibitor) in Recurrent KRAS-Mutant (KRAS-MT) and BRAF-Mutant (BRAF-MT) Non-Small Cell Lung Cancer (NSCLC) (RAMP 202)

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Trial Profile

A Phase 2 Study of Avutometinib (VS-6766) (Dual RAF/MEK Inhibitor) as a Single Agent and In Combination With Defactinib (FAK Inhibitor) in Recurrent KRAS-Mutant (KRAS-MT) and BRAF-Mutant (BRAF-MT) Non-Small Cell Lung Cancer (NSCLC) (RAMP 202)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 13 Mar 2024

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At a glance

  • Drugs Avutometinib (Primary) ; Defactinib (Primary)
  • Indications Non-small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms RAMP-202
  • Sponsors Verastem Oncology
  • Most Recent Events

    • 13 Mar 2024 This trial has been Discontinued in Spain (End date: 2023-12-12) according to European Clinical Trials Database record.
    • 08 Mar 2024 This trial has been Discontinued in Italy (End date: 2023-12-12) according to European Clinical Trials Database record.
    • 11 Jan 2024 Status changed from recruiting to completed.

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