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A Phase 2, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate Reduction in Inflammation in Patients With Advanced Chronic Renal Disease Utilizing Antibody-Mediated Interleukin-6 Inhibition in Japan

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Trial Profile

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate Reduction in Inflammation in Patients With Advanced Chronic Renal Disease Utilizing Antibody-Mediated Interleukin-6 Inhibition in Japan

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Oct 2022

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At a glance

  • Drugs Ziltivekimab (Primary)
  • Indications Cardiovascular disorders; Inflammation
  • Focus Therapeutic Use
  • Acronyms RESCUE-2
  • Sponsors Corvidia Therapeutics; Novo Nordisk

    • Most Recent Events

    • 29 Aug 2022 Primary endpoint has been met (The difference in the percent change in high-sensitivity C-reactive protein (hs-CRP) levels (average of all hs-CRP values prior to the administration of study drug) between each active group and placebo) , according to Results presented at the ESC Congress 2022 - Annual Congress of the European Society of Cardiology
    • 29 Aug 2022 Results presented at the ESC Congress 2022 - Annual Congress of the European Society of Cardiology
    • 26 Oct 2021 Status changed from recruiting to completed.
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