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A study analysing overall survival in BRAFV600 mutated metastatic NSCLC and Comparing Single Arm Dabrafenib+Trametinib Clinical Trial Outcomes with Real-World Standards of Care

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Trial Profile

A study analysing overall survival in BRAFV600 mutated metastatic NSCLC and Comparing Single Arm Dabrafenib+Trametinib Clinical Trial Outcomes with Real-World Standards of Care

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 18 Nov 2020

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At a glance

  • Drugs Carboplatin (Primary) ; Pembrolizumab (Primary) ; Pemetrexed (Primary) ; Antineoplastics; Dabrafenib/trametinib; Immunotherapies
  • Indications Non-small cell lung cancer
  • Focus Therapeutic Use
  • Most Recent Events

    • 18 Nov 2020 New trial record
    • 16 Nov 2020 Results comparing overall survival (OS) of dabrafenib/trametinib within the 3-year trial follow up ( NCT01336634) with a similar cohort of real world patients receiving first line pembrolizumab+carboplatin+pemetrexed, or second-line PD(L)1 monotherapy,presented at the 23rd Annual European Congress of the International Society for Pharmacoeconomics and Outcomes Research
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