Trial Profile

An Open Label, First in Human (FIH), Phase 1a/1b Trial of LVGN7409 (CD40 Agonist Antibody) as a Single Agent, in Combination With LVGN3616 (Anti-PD-1 Antibody), and in Combination With LVGN3616 and LVGN6051 (CD137 Agonist Antibody) in Patients With Locally Advanced, Relapsed, Refractory, or Metastatic Malignancy

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 22 May 2026

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At a glance

Drugs Dalnicastobart (Primary) ; Exlinkibart (Primary) ; Pradusinstobart (Primary)
Indications Cancer
Focus Adverse reactions; First in man
Sponsors Lyvgen Biopharma

19 May 2026 Status changed from active, no longer recruiting to completed.
31 Oct 2024 Planned End Date changed from 1 Jun 2024 to 31 Dec 2025.
31 Oct 2024 Planned primary completion date changed from 1 Jun 2024 to 31 Dec 2025.

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