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An Open Label, First in Human (FIH), Phase 1a/1b Trial of LVGN7409 (CD40 Agonist Antibody) as a Single Agent, in Combination With LVGN3616 (Anti-PD-1 Antibody), and in Combination With LVGN3616 and LVGN6051 (CD137 Agonist Antibody) in Patients With Locally Advanced, Relapsed, Refractory, or Metastatic Malignancy

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Trial Profile

An Open Label, First in Human (FIH), Phase 1a/1b Trial of LVGN7409 (CD40 Agonist Antibody) as a Single Agent, in Combination With LVGN3616 (Anti-PD-1 Antibody), and in Combination With LVGN3616 and LVGN6051 (CD137 Agonist Antibody) in Patients With Locally Advanced, Relapsed, Refractory, or Metastatic Malignancy

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 27 Jun 2023

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At a glance

  • Drugs Dalnicastobart (Primary) ; Exlinkibart (Primary) ; Pradusinstobart (Primary)
  • Indications Cancer
  • Focus Adverse reactions; First in man
  • Sponsors Lyvgen Biopharma

    • Most Recent Events

    • 22 Jun 2023 Planned End Date changed from 1 Dec 2023 to 1 Jun 2024.
    • 22 Jun 2023 Planned primary completion date changed from 1 Dec 2023 to 1 Jun 2024.
    • 07 Mar 2023 Planned End Date changed from 1 Apr 2023 to 1 Dec 2023.

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