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Phase 1b randomized, controlled chemoprotection trial in patients with p53-mutated advanced non-small cell lung cancer who are receiving first-line platinum-based chemotherapy

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Trial Profile

Phase 1b randomized, controlled chemoprotection trial in patients with p53-mutated advanced non-small cell lung cancer who are receiving first-line platinum-based chemotherapy

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 24 Jan 2025

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At a glance

  • Drugs ALRN 6924 (Primary) ; Carboplatin; Pemetrexed
  • Indications Chemotherapy-induced damage
  • Focus Registrational; Therapeutic Use

Most Recent Events

  • 10 Jan 2025 According to Rein Therapeutics media release, Aileron Therapeutics announces rebranding to Rein Therapeutics
  • 21 Feb 2023 According to an Aileron Therapeutics media release, based on the data from phase 1b breast cancer trial, company decided to terminate the further development of ALRN-6924.
  • 21 Feb 2023 Status changed from recruiting to discontinued, according to an Aileron Therapeutics media release.

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