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ATTAMAGE-A1.: Phase I/II Study of Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity MAGE-A1-Specific T-Cell Receptor (TCR) Combined With Atezolizumab in Patients With Metastatic MAGE-A1 Expressing Cancer

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ATTAMAGE-A1.: Phase I/II Study of Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity MAGE-A1-Specific T-Cell Receptor (TCR) Combined With Atezolizumab in Patients With Metastatic MAGE-A1 Expressing Cancer

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 05 Aug 2023

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At a glance

  • Drugs MAGE-A1-specific T cell receptor-transduced autologous T-cell therapy-SignalOne Bio (Primary) ; Atezolizumab; Cyclophosphamide; Fludarabine; Programmed cell death 1 receptor antagonists
  • Indications Advanced breast cancer; Carcinoma; Male breast cancer; Non-small cell lung cancer; Triple negative breast cancer; Urogenital cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms ATTAMAGE-A1

    • Most Recent Events

    • 09 Dec 2022 Status changed from suspended to discontinued.
    • 23 May 2022 Planned End Date changed from 1 Dec 2024 to 8 Apr 2023.
    • 23 May 2022 Planned primary completion date changed from 1 Dec 2024 to 8 Apr 2023.

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