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A Phase-II, Randomised, Double-blind, Parallel-group Trial to Investigate Emodepside (BAY 44-4400) in Subjects with Onchocerca volvulus Infection, comprising: Part 1 to Investigate Safety, Tolerability, Pharmacodynamics, Pharmacokinetics and Dose-Response Relationship for Efficacy (Proof-of-Concept); Part 2 to Investigate Efficacy of Selected Doses, Safety, Tolerability and Pharmacokinetics

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A Phase-II, Randomised, Double-blind, Parallel-group Trial to Investigate Emodepside (BAY 44-4400) in Subjects with Onchocerca volvulus Infection, comprising: Part 1 to Investigate Safety, Tolerability, Pharmacodynamics, Pharmacokinetics and Dose-Response Relationship for Efficacy (Proof-of-Concept); Part 2 to Investigate Efficacy of Selected Doses, Safety, Tolerability and Pharmacokinetics

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 08 Mar 2024

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At a glance

  • Drugs Emodepside (Primary) ; Ivermectin
  • Indications Onchocerciasis
  • Focus Adverse reactions; Proof of concept; Therapeutic Use

    • Most Recent Events

    • 04 Mar 2024 Status changed from not yet recruiting to active, no longer recruiting.
    • 30 Nov 2020 New trial record

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