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A Phase I/II, Open-label Study to Investigate the Pharmacokinetics, Safety, and Efficacyof ATG 016 Monotherapy in IPSS-R Intermediate Risk and Above Myelodysplastic Syndrome (MDS) Patients After Failure of Hypomethylating Agent (HMA)-Based Therapy

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Trial Profile

A Phase I/II, Open-label Study to Investigate the Pharmacokinetics, Safety, and Efficacyof ATG 016 Monotherapy in IPSS-R Intermediate Risk and Above Myelodysplastic Syndrome (MDS) Patients After Failure of Hypomethylating Agent (HMA)-Based Therapy

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 22 Apr 2024

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At a glance

  • Drugs Eltanexor (Primary)
  • Indications Myelodysplastic syndromes
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms HATCH
  • Sponsors Antengene Corporation
  • Most Recent Events

    • 15 Apr 2024 Status changed from active, no longer recruiting to discontinued.
    • 02 Aug 2023 Status changed from recruiting to active, no longer recruiting.
    • 03 May 2023 According to a Karyopharm Therapeutics media release, interim results from the phase 2 portion of this study presented at the 17th International Congress on MDS

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