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An Open-Label, Multicenter Phase 1b/2 Study of Nanatinostat and Valganciclovir in Patients with Advanced Epstein-Barr Virus-Positive (EBV+) Solid Tumors and in Combination with Pembrolizumab in Patients with Recurrent/Metastatic Nasopharyngeal Carcinoma

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Trial Profile

An Open-Label, Multicenter Phase 1b/2 Study of Nanatinostat and Valganciclovir in Patients with Advanced Epstein-Barr Virus-Positive (EBV+) Solid Tumors and in Combination with Pembrolizumab in Patients with Recurrent/Metastatic Nasopharyngeal Carcinoma

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 21 Jan 2025

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At a glance

  • Drugs Nanatinostat/valganciclovir combination therapy (Primary) ; Pembrolizumab (Primary) ; Valganciclovir (Primary)
  • Indications Carcinoma; Gastric cancer; Leiomyosarcoma; Nasopharyngeal cancer; Solid tumours
  • Focus Adverse reactions; Proof of concept; Therapeutic Use
  • Sponsors Viracta Therapeutics

    • Most Recent Events

    • 10 Jan 2025 Status changed from active, no longer recruiting to discontinued.
    • 10 Jan 2025 According to ClinicalTrials.gov: US National Institutes of Health, Terminated due to Sponsor Decision
    • 01 Oct 2024 According to a Viracta Therapeutics media release, the company determined the recommended Phase 2 dose in patients with advanced EBV+ solid tumors.

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