Trial Profile

ChariotMS A national (UK), multi-centre, randomised, double-blind, placebo-controlled (1:1) phase IIb efficacy trial with cost-utility analysis of cladribine tablets (3.5mg/kg over two years) in people with advanced multiple sclerosis (EDSS 6.5-8.5). Is cladribine superior to placebo in protecting upper limb function?

Status: Active, no longer recruiting

Phase of Trial: Phase II/III

Latest Information Update: 07 Oct 2025

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At a glance

17 Sep 2025 According to an EMD Serono media release, data fromthis study presented at the 41st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), being held September 24-26 in Barcelona.
08 Sep 2025 Status changed from recruiting to active, no longer recruiting.
02 Dec 2024 Planned primary completion date changed from 31 Oct 2024 to 31 Dec 2024.

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