A Phase 3 Open-Label, Randomized Study of Fixed Duration Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab Versus Venetoclax and Rituximab in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (BRUIN CLL-322)
Latest Information Update: 09 Mar 2026
At a glance
- Drugs Pirtobrutinib (Primary) ; Rituximab; Venetoclax
- Indications Chronic lymphocytic leukaemia
- Focus Registrational; Therapeutic Use
- Acronyms BRUIN CLL-322
- Sponsors Loxo Oncology
Most Recent Events
- 29 Jan 2026 Planned End Date changed from 1 Jan 2027 to 1 Oct 2027.
- 29 Jan 2026 Planned primary completion date changed from 1 Apr 2026 to 1 Oct 2026.
- 19 Nov 2024 Status changed from recruiting to active, no longer recruiting.