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Phase 1b/2 Clinical Study of the Safety, Tolerability, and Pharmacokinetic and Pharmacodynamic Profiles of CFI-400945 as a Single Agent or in Combination With Azacitidine in Patients With AML, MDS or CMML

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Trial Profile

Phase 1b/2 Clinical Study of the Safety, Tolerability, and Pharmacokinetic and Pharmacodynamic Profiles of CFI-400945 as a Single Agent or in Combination With Azacitidine in Patients With AML, MDS or CMML

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 09 Feb 2024

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At a glance

  • Drugs Azacitidine (Primary) ; Decitabine (Primary) ; Ocifisertib (Primary)
  • Indications Acute myeloid leukaemia; Chronic myelomonocytic leukaemia; Myelodysplastic syndromes
  • Focus Adverse reactions
  • Sponsors Treadwell Therapeutics
  • Most Recent Events

    • 02 Feb 2024 Planned End Date changed from 1 Jan 2024 to 1 Jan 2026.
    • 02 Feb 2024 Planned primary completion date changed from 1 Jan 2024 to 1 Jan 2026.
    • 15 Dec 2023 According to a Treadwell Therapeutics media release, company looking forward into dose expansion studies in monotherapy and in combination in 2024.

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