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A Phase 3, Multi-Center, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy and Safety of CK-3773274 in Adults With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction

Trial Profile

A Phase 3, Multi-Center, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy and Safety of CK-3773274 in Adults With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 11 May 2026

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At a glance

  • Drugs Aficamten (Primary)
  • Indications Hypertrophic cardiomyopathy
  • Focus Registrational; Therapeutic Use
  • Acronyms SEQUOIA-HCM
  • Sponsors Cytokinetics

Most Recent Events

  • 28 Apr 2026 According to a Cytokinetics media release, data from this trial will be presented at the European Society of Cardiology Heart Failure 2026 Congress taking place in Barcelona, Spain, from May 9-12, 2026.
  • 16 Mar 2026 Results presented in the Cytokinetics Media Release.
  • 16 Mar 2026 According to a Cytokinetics media release, data from analysis of this study will be presented in a Poster Presentation, March 29, 2026, 2PM-3PM CT at the American College of Cardiology (ACC) Annual Scientific Session & Expo taking place March 28-30, 2026 in New Orleans, LA.

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