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Efficacy and Safety of Tirzepatide Once Weekly Versus Placebo for Maintenance of Weight Loss in Participants Without Type 2 Diabetes Who Have Obesity or Are Overweight With Weight-Related Comorbidities: A Randomized, Double-Blind, Placebo-Controlled Trial (SURMOUNT-4)

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Trial Profile

Efficacy and Safety of Tirzepatide Once Weekly Versus Placebo for Maintenance of Weight Loss in Participants Without Type 2 Diabetes Who Have Obesity or Are Overweight With Weight-Related Comorbidities: A Randomized, Double-Blind, Placebo-Controlled Trial (SURMOUNT-4)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 28 Aug 2024

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At a glance

  • Drugs Tirzepatide (Primary)
  • Indications Obesity
  • Focus Registrational; Therapeutic Use
  • Acronyms SURMOUNT-4
  • Sponsors Eli Lilly and Company

    • Most Recent Events

    • 11 Dec 2023 Results presented in an Eli Lilly and Company media release.
    • 11 Dec 2023 Results (n=670) assessing the effect of tirzepatide, with diet and physical activity, on the maintenance of weight reduction, published in the JAMA: the Journal of the American Medical Association.
    • 27 Jul 2023 according to an Eli Lilly and Company Media Release , the full results of the SURMOUNT-4 study will be published at the European Association for the Study of Diabetes Annual Meeting in October and submitted for publication in a peer-reviewed journal.

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