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A Phase III Randomized, Controlled, Multicenter, Open-label Study of ATG-010, Bortezomib, and Dexamethasone (SVd) Versus Bortezomib and Dexamethasone (Vd) in Patients With Relapsed or Refractory Multiple Myeloma (RRMM)

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Trial Profile

A Phase III Randomized, Controlled, Multicenter, Open-label Study of ATG-010, Bortezomib, and Dexamethasone (SVd) Versus Bortezomib and Dexamethasone (Vd) in Patients With Relapsed or Refractory Multiple Myeloma (RRMM)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 26 Jul 2023

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At a glance

  • Drugs Selinexor (Primary) ; Bortezomib; Dexamethasone
  • Indications Multiple myeloma
  • Focus Registrational; Therapeutic Use
  • Acronyms BENCH
  • Sponsors Antengene Corporation
  • Most Recent Events

    • 10 Jul 2023 Status changed from recruiting to active, no longer recruiting.
    • 18 Mar 2022 According to an Antengene Corporation media release, enrollment is expected to complete in 2022.
    • 17 Dec 2021 According to a Karyopharm Therapeutics media release, based on data from STORM and MARCH trial, the China NMPA has granted conditional approval for marketing in china for selinexor in combination with dexamethasone in patients with relapsed or refractory multiple myeloma who have received prior therapies and whose disease is refractory to at least a proteasome inhibitor, and an anti-CD38 monoclonal antibody. The Bench trial will serve as the confirmatory trial.
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