Trial Profile

Vitrectomy, Subretinal Tissue Plasminogen Activator and Intravitreal Gas for Submacular Haemorrhage Secondary to Exudative Age-Related Macular Degeneration (TIGER): a Phase 3, Pan-European, Two-group, Observer-masked, Superiority, Randomised Controlled Surgical Trial

Status: Recruiting

Phase of Trial: Phase III

Latest Information Update: 20 Aug 2025

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At a glance

06 Aug 2025 Planned End Date changed from 1 Dec 2025 to 1 Dec 2028.
06 Aug 2025 Planned primary completion date changed from 1 Jan 2025 to 1 Dec 2028.
14 Apr 2025 Protocol amendments updates including 1.Addition of other brand of medication Alteplase, 2.Baseline treatments for participants in control group, 3.Secondary outcome measure,and 4.Treatment Additional injections of aflibercept. has been published in the Trials.

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