Vitrectomy, Subretinal Tissue Plasminogen Activator and Intravitreal Gas for Submacular Haemorrhage Secondary to Exudative Age-Related Macular Degeneration (TIGER): a Phase 3, Pan-European, Two-group, Observer-masked, Superiority, Randomised Controlled Surgical Trial
Latest Information Update: 20 May 2025
At a glance
- Drugs Aflibercept (Primary) ; Alteplase; Sulfur hexafluoride
- Indications Haemorrhage; Wet age-related macular degeneration
- Focus Therapeutic Use
- Acronyms TIGER
Most Recent Events
- 14 Apr 2025 Protocol amendments updates including 1.Addition of other brand of medication Alteplase, 2.Baseline treatments for participants in control group, 3.Secondary outcome measure,and 4.Treatment Additional injections of aflibercept. has been published in the Trials.
- 14 Apr 2025 Protocol amendment updates from this trial were published in the Trials.
- 31 Jan 2022 Status changed from not yet recruiting to recruiting.