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A Multicenter, Open-label, Single-arm, Expanded Access Protocol of Sotorasib for the Treatment of Subjects With Previously Treated Locally Advanced Unresectable/Metastatic NSCLC With KRAS p.G12C Mutation

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Trial Profile

A Multicenter, Open-label, Single-arm, Expanded Access Protocol of Sotorasib for the Treatment of Subjects With Previously Treated Locally Advanced Unresectable/Metastatic NSCLC With KRAS p.G12C Mutation

Status: Completed
Phase of Trial: Clinical Phase Unknown

Latest Information Update: 28 Aug 2023

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At a glance

  • Drugs Sotorasib (Primary)
  • Indications Brain metastases; Non-small cell lung cancer
  • Focus Adverse reactions; Expanded access
  • Acronyms pINN Sotorasib
  • Sponsors Amgen

Most Recent Events

  • 23 Aug 2023 Status changed from recruiting to completed.
  • 13 Sep 2022 Results of first analysis reporting safety and efficacy data from 2 global protocols under the EAP (20190436 and 20190442) presented at the 47th European Society for Medical Oncology Congress
  • 17 Dec 2020 New trial record

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