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A Randomized, Double-blind, Placebo-Controlled, Dose-Ranging Multicenter Study to Evaluate the Efficacy and Safety of ALN-AGT01 in Patients With Mild-to-Moderate Hypertension

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Trial Profile

A Randomized, Double-blind, Placebo-Controlled, Dose-Ranging Multicenter Study to Evaluate the Efficacy and Safety of ALN-AGT01 in Patients With Mild-to-Moderate Hypertension

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 15 Jul 2024

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At a glance

  • Drugs Zilebesiran (Primary)
  • Indications Hypertension
  • Focus Therapeutic Use
  • Acronyms KARDIA-1
  • Sponsors Alnylam Pharmaceuticals

    • Most Recent Events

    • 01 Jul 2024 Planned End Date changed from 4 Dec 2024 to 5 Dec 2024.
    • 08 Apr 2024 Results of subgroup analysis assessing zilebesiran efficacy and safety presented at the 73rd Annual Scientific Session of the American College of Cardiology
    • 07 Apr 2024 According to an Alnylam Pharmaceuticals media release, results form subgroup from this trial were presented at the 2024 American College of Cardiology (ACC) Annual Scientific Session.

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