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A Single-center, Open-label, Fixed-sequence Phase I Drug-drug Interaction Clinical Study to Investigate the Pharmacokinetics of SHR3680 With Midazolam CYP3A4 Substrates), S-Warfarin (CYP2C9 Substrates) and Omeprazole (CYP2C19 Substrates) in Prostate Cancer Patients

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A Single-center, Open-label, Fixed-sequence Phase I Drug-drug Interaction Clinical Study to Investigate the Pharmacokinetics of SHR3680 With Midazolam CYP3A4 Substrates), S-Warfarin (CYP2C9 Substrates) and Omeprazole (CYP2C19 Substrates) in Prostate Cancer Patients

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 14 Feb 2023

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At a glance

  • Drugs Rezvilutamide (Primary) ; Midazolam; Omeprazole; Phytomenadione; Warfarin
  • Indications Adenocarcinoma; Prostate cancer
  • Focus Pharmacokinetics
  • Sponsors Jiangsu Hengrui Medicine Co.

    • Most Recent Events

    • 08 Feb 2023 Status changed from recruiting to completed.
    • 23 Dec 2020 New trial record

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