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A Phase 1, Open-Label, Multicenter Trial Investigating the Safety, Tolerability, and Preliminary Antineoplastic Activity of Sym024 (Anti-CD73) as Monotherapy and in Combination With Sym021 (Anti-PD-1) in Patients With Advanced Solid Tumor Malignancies

Trial Profile

A Phase 1, Open-Label, Multicenter Trial Investigating the Safety, Tolerability, and Preliminary Antineoplastic Activity of Sym024 (Anti-CD73) as Monotherapy and in Combination With Sym021 (Anti-PD-1) in Patients With Advanced Solid Tumor Malignancies

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 11 Dec 2024

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At a glance

  • Drugs Sym 021 (Primary) ; Sym 024 (Primary)
  • Indications Adenocarcinoma; Carcinoma; Cholangiocarcinoma; Colorectal cancer; Gastric cancer; Head and neck cancer; Mesothelioma; Non-small cell lung cancer; Oesophageal cancer; Pancreatic ductal carcinoma; Peritoneal cancer; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions; First in man
  • Sponsors Symphogen

Most Recent Events

  • 09 Dec 2024 Status changed from active, no longer recruiting to completed.
  • 18 Apr 2024 Planned End Date changed from 1 Jul 2024 to 1 Dec 2024.
  • 18 Apr 2024 Planned primary completion date changed from 1 Jul 2024 to 1 Dec 2024.

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