Trial Profile

Randomized, Double-Blind, Placebo-controlled Safety Study of Glial Cell Line-Derived Neurotrophic Factor Gene Transfer (AAV2-GDNF) in Multiple System Atrophy

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 30 May 2025

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At a glance

Drugs AB 1005 (Primary)
Indications Multiple system atrophy
Focus Adverse reactions
Acronyms REGENERATE
Sponsors Brain Neurotherapy Bio

Most Recent Events

17 Nov 2023 According to a Asklepios BioPharmaceutical media release, the first patient has been randomized at the Ohio State University Wexner Medical Center in this trial.
13 Oct 2023 Planned End Date changed from 1 Mar 2026 to 1 Dec 2028.
13 Oct 2023 Planned primary completion date changed from 1 Mar 2024 to 1 Dec 2025.

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