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A Phase 1 Study to Evaluate IL13Rα2-Targeted Chimeric Antigen Receptor (CAR) T Cells for Adult Patients With Leptomeningeal Glioblastoma, Ependymoma or Medulloblastoma

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Trial Profile

A Phase 1 Study to Evaluate IL13Rα2-Targeted Chimeric Antigen Receptor (CAR) T Cells for Adult Patients With Leptomeningeal Glioblastoma, Ependymoma or Medulloblastoma

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 24 Feb 2026

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At a glance

  • Drugs MB 101 (Primary)
  • Indications Ependymoma; Glioblastoma; Medulloblastoma
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 20 Feb 2026 Planned End Date changed from 17 Nov 2025 to 12 Jan 2027.
  • 20 Feb 2026 Planned primary completion date changed from 17 Nov 2025 to 12 Jan 2027.
  • 03 Jun 2025 Status changed from recruiting to active, no longer recruiting.

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