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A Multicenter, Multiple-Dose Study in Neovascular Age-related Macular Degeneration (nAMD) to Evaluate the Safety, Tolerability, Pharmacodynamics, Immunogenicity, and Clinical Effect of Repeat Intravitreal (IVT) Injections of GEM103 as an Adjunct to Standard of Care Aflibercept Therapy

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A Multicenter, Multiple-Dose Study in Neovascular Age-related Macular Degeneration (nAMD) to Evaluate the Safety, Tolerability, Pharmacodynamics, Immunogenicity, and Clinical Effect of Repeat Intravitreal (IVT) Injections of GEM103 as an Adjunct to Standard of Care Aflibercept Therapy

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 04 Nov 2022

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At a glance

  • Drugs Recombinant complement factor H Gemini Therapeutics (Primary) ; Aflibercept
  • Indications Choroidal neovascularisation; Wet age-related macular degeneration
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Gemini Therapeutics

    • Most Recent Events

    • 04 Oct 2022 Status changed from completed to discontinued.
    • 22 Mar 2022 Status changed from active, no longer recruiting to completed.
    • 10 Jan 2022 Results published in the Media Release

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