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Phase II Study of Pembrolizumab and Ablative Radiotherapy With or Without Olaparib in Metastatic Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancers : Initial Test Cohorts of a Platform Trial to Sequentially Investigate Immunotherapy Combinations for the Augmentation of Immune Responses

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Phase II Study of Pembrolizumab and Ablative Radiotherapy With or Without Olaparib in Metastatic Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancers : Initial Test Cohorts of a Platform Trial to Sequentially Investigate Immunotherapy Combinations for the Augmentation of Immune Responses

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 09 Oct 2023

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At a glance

  • Drugs Olaparib (Primary) ; Pembrolizumab (Primary)
  • Indications Advanced breast cancer; HER2 negative breast cancer; Triple negative breast cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 19 Oct 2022 Planned number of patients changed from 56 to 34.
    • 21 Apr 2021 Status changed from not yet recruiting to recruiting.
    • 01 Mar 2021 Planned initiation date changed from 1 Jan 2021 to 1 Jun 2021.
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