Trial Profile

A Phase I/II Study of PI3Kγδ Inhibitor Duvelisib in Combination With Nivolumab in Patients With Advanced Unresectable Melanoma Who Have Progressed on Anti-PD1 Therapy

Status: Discontinued

Phase of Trial: Phase I/II

Latest Information Update: 21 Dec 2025

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At a glance

Drugs Duvelisib (Primary) ; Nivolumab (Primary)
Indications Malignant melanoma
Focus Adverse reactions; Therapeutic Use

Most Recent Events

17 Dec 2025 Status changed from active, no longer recruiting to discontinued because Secura Bio discontinued supporting this trial.
08 Aug 2024 Planned End Date changed from 1 Oct 2029 to 1 Dec 2028.
08 Aug 2024 Status changed from recruiting to active, no longer recruiting.

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