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A Phase 2a trial of niclosamide (FW-420) for the treatment of for Grade 1 and Grade 2 immune checkpoint inhibitor-associated colitis (ICI-AC) and diarrhea in oncology patients

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Trial Profile

A Phase 2a trial of niclosamide (FW-420) for the treatment of for Grade 1 and Grade 2 immune checkpoint inhibitor-associated colitis (ICI-AC) and diarrhea in oncology patients

Status: Planning
Phase of Trial: Phase II

Latest Information Update: 29 May 2024

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At a glance

  • Drugs Niclosamide (Primary)
  • Indications Colitis; Diarrhoea
  • Focus Adverse reactions
  • Acronyms PASSPORT
  • Most Recent Events

    • 16 May 2024 According to an Entero Therapeutics media release, First Wave Biopharma has changed its name to Entero Therapeutics.
    • 16 Nov 2021 According to a First Wave Biopharma media release, the company expect to initiate this trial in 2022.
    • 21 Oct 2021 According to a First Wave Biopharma media release, the committee members also include 4) David Faleck, M.D., Assistant Professor of Medicine at Weill Medical College and an attending physician in the Gastroenterology, Hepatology and Nutrition Service at Memorial Sloan Kettering Cancer Center (MSK).

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