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Brolucizumab Switch and Extend Ph IIIb Study: A Canadian, Multi-center, Single-arm, Open Label Study Assessing the Efficacy and Safety of Brolucizumab 6mg in a Treat and Extend Regimen in Patients With Neovascular Age-Related Macular Degeneration (nAMD) With Prior Anti-VEGF Exposure (PEREGRINE)

Trial Profile

Brolucizumab Switch and Extend Ph IIIb Study: A Canadian, Multi-center, Single-arm, Open Label Study Assessing the Efficacy and Safety of Brolucizumab 6mg in a Treat and Extend Regimen in Patients With Neovascular Age-Related Macular Degeneration (nAMD) With Prior Anti-VEGF Exposure (PEREGRINE)

Status: Withdrawn prior to enrolment
Phase of Trial: Phase III

Latest Information Update: 02 Nov 2021

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At a glance

  • Drugs Brolucizumab (Primary) ; Aflibercept
  • Indications Wet age-related macular degeneration
  • Focus Registrational; Therapeutic Use
  • Acronyms PEREGRINE
  • Sponsors Novartis Pharmaceuticals

Most Recent Events

  • 12 Jul 2021 Planned End Date changed from 31 May 2025 to 21 Jun 2021.
  • 12 Jul 2021 Planned initiation date changed from 28 Feb 2021 to 31 May 2021.
  • 12 Jul 2021 Status changed from recruiting to withdrawn prior to enrolment since no participants were enrolled.

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