Phase 1/1B Study of DS-8201a in Combination With ATR Inhibition (AZD6738) in Advanced Solid Tumors With HER2 Expression (DASH Trial)
Latest Information Update: 11 Oct 2024
At a glance
- Drugs Ceralasertib (Primary) ; Trastuzumab-deruxtecan (Primary)
- Indications Adenocarcinoma; Advanced breast cancer; Biliary cancer; Colon cancer; Colorectal cancer; Endometrial cancer; Gastric cancer; Liver cancer; Oesophageal cancer; Salivary gland cancer; Solid tumours
- Focus Adverse reactions; Biomarker; Pharmacodynamics
- Acronyms DASH trial
- 06 Jun 2024 Planned number of patients changed from 15 to 51.
- 02 Jul 2021 Status changed from not yet recruiting to recruiting.
- 02 Jul 2021 Planned End Date changed from 8 Mar 2023 to 31 Mar 2026.