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A Phase 1, Single-center, Open-label Study to Assess the Intrapulmonary Pharmacokinetics of SPR859 by Comparing the Plasma, Epithelial Lining Fluid (ELF), and Alveolar Macrophages (AM) Concentrations Following the Oral Administration of Five Doses of SPR994 in Healthy, Nonsmoking Volunteers

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Trial Profile

A Phase 1, Single-center, Open-label Study to Assess the Intrapulmonary Pharmacokinetics of SPR859 by Comparing the Plasma, Epithelial Lining Fluid (ELF), and Alveolar Macrophages (AM) Concentrations Following the Oral Administration of Five Doses of SPR994 in Healthy, Nonsmoking Volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 04 Jul 2022

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At a glance

  • Drugs Tebipenem pivoxil (Primary)
  • Indications Gram-negative infections
  • Focus Pharmacokinetics
  • Sponsors Spero Therapeutics

    • Most Recent Events

    • 28 Jun 2022 Results published in the Antimicrobial Agents and Chemotherapy
    • 21 Apr 2022 According to a Spero Therapeutics media release, data from this trial will be presented at the 32nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 2022.
    • 15 Mar 2021 Status changed from recruiting to completed.

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