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Open-label, Phase 1b, Single-ascending Dose and Optional re Dosing Study to Evaluate the Safety of VERVE-101 Administered to Patients With Heterozygous Familial Hypercholesterolemia, Atherosclerotic Cardiovascular Disease, and Uncontrolled Hypercholesterolemia

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Open-label, Phase 1b, Single-ascending Dose and Optional re Dosing Study to Evaluate the Safety of VERVE-101 Administered to Patients With Heterozygous Familial Hypercholesterolemia, Atherosclerotic Cardiovascular Disease, and Uncontrolled Hypercholesterolemia

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 11 Apr 2024

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At a glance

  • Drugs VERVE-101 (Primary)
  • Indications Hypercholesterolaemia; Hyperlipoproteinaemia type II
  • Focus Adverse reactions; First in man; Proof of concept
  • Acronyms Heart-1
  • Sponsors Verve Therapeutics

    • Most Recent Events

    • 05 Apr 2024 Status changed from recruiting to active, no longer recruiting.
    • 13 Nov 2023 Interim Results presented in patients with HeFH and pre-existing ASCVD, at the American Heart Association Scientific Sessions 2023
    • 12 Nov 2023 According to a Verve Therapeutics media release, data from this trial were presented at the American Heart Association's Scientific Sessions 2023.

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